Fatigue is one of the commonest presenting symptoms in clinical setting which affects daily physical activity and functioning. It is a complex phenomenon in terms of definition, dimension, behavior, measurement and mechanism etc. In Unani medicine it has been described as Aa'iya which primarily occurs as physiological phenomenon due to excessive exertion. Dalak (Massage) is said to be an effective regimen in the relief of Aa’iya. Although the regimen is used widely in various clinical problems but there are very few documentary evidences to support the claim. This study investigates the efficacy of Dalak (Massage) application in Aa’iya (Fatigue). It was an open interventional study in which 50 patients were included. After obtaining informed consent the set protocol of Dalak-e-Isterdad (Restorative Light Massage) was given for 10 days. Aa’iya (Fatigue) was diagnosed through questionnaire based Visual Analogue Scale (VAS) and Fatigue Severity Scale (FSS). The assessments were recorded on 1st, 5th and 10th days. The difference was compared and analyzed statistically for significance.

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