afoof-e-Barangi (SB) is a Unani polyherbal powder formulation used to treat Deedan-e-Ama (intestinal worm) since a long time. The objective of the study is to establish the standardization of SB by using scientific analytical procedures. In this study SB is evaluated for its various organoleptic and physico-chemical parameters. SB is buckthorn brown, odorless and bitter in taste. The physico-chemical parameters are expressed as mean values of the loss of weight on drying, total ash, acid insoluble ash and water soluble ash as 4.82± 0.18, 4.05 ± 0.24, 2.80 ± 0.14 and 1.30±0.06 respectively. The mean values of bulk density, tapped density, angle of repose, Hausner’s ratio and compressibility index were 0.5481 ± 0.0042, 0.6922 ± 0.0026, 35.47± 1.02°, 1.278 ± 0.022o and 20.7887 ± 0.6785 respectively, pH of 1% and 10% solution were 4.9 ± 0.1 and 5.5 ± 0.1 respectively. Extractive values in petroleum ether, benzene and ethyl alcohol by successive extraction method were 2.07 ± 0.13, 1.02 ± 0.04 and 12.86 ± 0.35 respectively. Extractive values in petroleum ether, benzene and ethyl alcohol by non-successive extraction method were 2.07 ± 0.13, 2.40 ± 0.30, and 13.18 ± 0.35 respectively. Qualitative analysis showed the presence of all major organic constituents except proteins, saponins and steroids.