Qurs-e-Mafasil Jadeed mentioned in Qarabadeen-e-Majeedi, is a compound preparation used in joint diseases, but has not been standardized so far. In the present study the standardization on the basis of physico-chemical and analytical parameters, laid down by Unani Pharmacopoeial Committee was carried out. The parameters studied included Organoleptic properties (colour, texture, taste and smell) of tablet, Disintegration time, Friability, Alcohol and water soluble content, Moisture content, Loss of weight on drying, Ash values, pH values and TLC. Thus, the present study determined the value of the parameters of standardization for the Unani, pharmacopoeal compound preparation, Qurs-e-Mafasil Jadeed for the first time. The disintegration time and friability were found to be within acceptable limits. This data can be pooled with the study of other samples in order to propose the pharmacopoeal standards for the Qurs-e-Mafasil Jadeed.