Nelumbo nucifera Gaertn. is equated to botanical source of ‘Kamala’. This plant species is attributed for various medicinal properties and its different morphological parts viz. rhizome and seeds are edible. The present study is carried out on the pharmacognostical standardization of Nelumbo nucifera Gaertn. (seeds) along with Thin- Layer chromatographic profile which is aimed to develop quality standards for the drug.