iabetes mellitus is such a complex disorder that affects the histological, biochemical as well as haemorrheological components of the body and its fluids, resulting from number of factors in which an absolute or relative deficiency of insulin or its function usually present. It has been observed that Diabetes mellitus directly affects the haemorrheological properties in addition to other pathologies. All blood constituents viz. RBCs, WBCs, Platelets and Plasma are modified in such a way that they lead to hypoxia, acidosis, capillary damage and microvascular disease. Haemodilution, the most vital measure to increase the fluidity of blood, is a way of rheological therapeutics which enhances the perfusion at multiple organ sites. This can be achieved by administration of various potential Unani drugs. This phenomenon also approves the concept of Jilain Rooh to heal up the body and mind. The aim of rheological intervention through Unani drugs is to improve the blood circulation under driving forces which has become stagnated due to either reasons. This stagnation usually caused by rauleux formation, cell deformity and changes in viscosity. Unani drugs are reported to produce haemodilution which corrects the hypoxia, haematocrit, viscosity, cellular aggregation and rigidity to enable the microcirculation to be restored. The paper deals in details, how the diabetic microangiopathies take place and by exploiting the repository of Unani drugs the haemorrheological disturbances can be corrected, which is indispensable in the management of this condition.