Abortion is the ending of pregnancy by expulsion of the fetus or embryo from the womb before reaching the viability to survive. It is a sensitive and very distressing, sad situation for the expecting mother and is also contentious issue with religious, moral, cultural and political dimensions. In Unani System of Medicine it is known as “Isqate Hamal or Isqate Janeen”. It is the commonest problem in obstetrics, which is studied from the early era of medicine till now. Almost every Unani physician has described about the causes and preventive measures of abortion. They were mainly focused on prevention of abortion by various non-pharmacological and pharmacological methods. Non- pharmacological methods like bed rest, avoidance of jerky movements etc; whereas pharmacological methods include systemic use of astringent drugs both single and compound formulations as well as local applications, which are very effective in the management of abortion are recommended. The literature of Unani medicine has wealth of treasure on abortion, but the issue is not in a systemic way. Hence, in this review scattered knowledge and description about the abortion and its consequences has been systematized in an easy way. An attempt has been made to systematically review the literature on abortion and to make the reader familiar with the contributions of Unani physicians.