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A Clinical Study of the Unani Formulation UNIM-045 for Anti-Vitiligo effect

Radhey Shyam Verma, Pervez Khan, Mohd. Naseem and Latafat Ali Khan

Hippocratic Journal of Unani Medicine
Hippocratic Journal of Unani Medicine January - March 2012, Vol. 7 No. 2, Pages 31-40


Leucoderma, a Latin word, meaning “white skin” is caused by the destruction of melanocytes; the cells responsible for skin colour. Out of 23 patients studied, 6 patients showed 40% pigmentation, 8 patients showed 41 to 70 % pigmentation, 8 patients showed 71 to 90 %

pigmentation and 1 patient showed complete pigmentation affected on different

parts of the body. All the biochemical and haematological parameters were done by the standard methods referred in the text. In biochemical studies a significant reduction on the levels of Serum Total Protein (P<0.001) and Serum Albumin (P<0.01); however UNIM-045 significantly increase the levels of Serum Globulin (P<0.01); and A/G ratio (P<0.01) in different follow-up in Bars patients (Table-1). UNIM-045 significantly reduced the levels of Serum Glutamate Pyruvate Transaminase (SGPT) (P<0.001) and Serum Glutamate Oxaloacetate Transaminase (SGOT) (P<0.001) whereas a significant increases in the levels of Serum Alkaline Phosphatase enzyme, within normal level (P<0.001) (Table-2) were observed when compared with pre-treatment to the different follow-up. In haematological studies a significant decrease in the levels of Erythrocyte Sedimentation Rate (ESR) (P<0.01), Red Blood Corpuscles (RBC) (P<0.01) (Ist and IInd Follow-up) and Total Leucocytes Counts (TLC) (P<0.05) (IInd follow-up) (Table-3) were observed, when compared with pre-treatment to different follow-up in bars (vitiligo) patients. Thus test Unani formulation is suggested to have anti-Vitiligo effect (As shown in Fig-1 photographs).

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