Standardization of Unani Drug – Jawarish Usquf

Mageswari, D. Ramasamy, P. Meera Devi Sri, Rampratap Meena, Shamsul Arfin, Aminuddin and Jameeluddin Ahmed

Hippocratic Journal of Unani Medicine

Hippocratic Journal of Unani Medicine October - December 2014, Vol. 9 No. 4, Pages 135-144

Abstract

The drug Jawarish Usquf is therapeutically used in the ailments of Munaqqi-e-Asab, Laqwa and Qulanj. Jawarish Usquf was prepared in three different batches as per the guidelines of NFUM (Part-IV). Present study was aimed to evaluate the powder microscopical studies to identify the raw drugs present in the formulation, physico-chemical data to lay down pharmacopoeial standards, TLC to develop the fingerprints and WHO parameters to ascertain quality of the drug. Powder microscopical studies showed the presence of numerous starch grains, non-lignified septate fibres, reticulate vessels (Zanjabeel); fibres lignified not over 30μ breadth, stone cells horse shoe shaped (Darchini); large mesocarpic parenchyma cells with corner thickening (Aamla); pollen grains tetrahedral upto 20ì, fragments of anther wall (Qaranfal); tracheidal cells with scalariform thickening upto 50μ (Bisfayej); endosperm cells filled with starch grains and crystalloid proteins (Jauzbuwa); perisperm cells with angular walls filled with starch grains (Filfil Siyah); group of bulbous perisperm cells packed with starch grains (Heel Kalan); vessels with pitted thickening; rosette of calcium oxalate crystals (Turbud). The physico-chemical data showed that the drug contains moisture (18.51%), total ash (0.69%), acid in-soluble ash (0.022%) solubility in alcohol (25.46%) and water (64.55%). TLC study showed various spots at 254nm, 366nm and visible light (V-S reagent). The quality control study revealed the absence of microbial load, aflatoxins, heavy metal and pesticide residues. The evaluated standards will be much useful for laying down the pharmacopoeial standards of Jawarish Usquf and also in providing the quality medicine to the needy mass.

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