Standardization of Laooq-e-Khiyarshambar- A Classical Unani Formulation
Rampratap Meena, D. Ramasamy, Asma Sattar Khan, Shoeb Ahmed Ansari, Shamsul Arfin and Aminuddin
Hippocratic Journal of Unani Medicine
Hippocratic Journal of Unani Medicine April - June 2015, Vol. 10 No. 2, Pages 111-121
Standardization of Unani herbal formulations is very much essential to justify the quality of a medicine. Unani medicines have played a significant role in maintaining of human health. These medicines are accepted as important therapeutic agents for the treatment of various kinds of diseases. But in many instances, it has been noticed that incorrect raw materials have been added in the formulations which has resulted adulterated product in market place. The Unani medicine Laooq-e-Khiyarshambar is an important polyherbal Unani medicine is being used in the ailments of catarrh, coryza, bronchitis and constipation. The drug Laooq-e-Khiyarshamber was standardized using standard methods such as pharmacognostical, physico-chemical and TLC/HPTLC. The other parameters like microbial load, heavy metals, aflatoxins and pesticide residues were also analyzed to ascertain the quality of medicine. The physico- chemical data such as moisture content was 19.23%. Alcohol soluble extractives 22.68% and water soluble extractive 69.61% shows presence of polar compound and inorganic material respectively. The content of total ash was 1.50% and acid insoluble ash 0.07% shows negligible amount of siliceous matter present in the drug. HPTLC finger print of chloroform and alcohol extracts shows13and 9 peaks with the developing systems toluene: ethyl acetate 8.5: 1.5and 6:4 respectively. The data evolved can be adopted for laying down the pharmacopoeial standards and TLC/HPTLC finger prints of the drug Laooq-e-Khiyarshamber.