Redesigning of the Unani Preparation from Powder Form into Tablet and its Standardization Along with HPLC Profile

Aziz ur Rahman and Tajuddin

Hippocratic Journal of Unani Medicine

Hippocratic Journal of Unani Medicine January - March 2015, Vol. 10 No. 1, Pages 31-42

Abstract

ablet is one of the most suitable and preferred solid dosage form used all over the world. Almost all drug molecules can be formulated as a tablet and the process of manufacturing of tablets is very simple, and flexible. One can administer 0.01 mg to 1 gm of a drug as a tablet by the oral route. Therefore, in the present study an anti-arthritic pharmacopoeial preparation in powder form having ingredients Suranjan Talkh(Colchicum luteum), Zanjabeel Khushk (Zingiber officinale) and Elwa (Aloe vera) were re-designed and modified for use in the form of Tablet (Qurs) and standardized. Organoleptic characters of tablet, tests for weight variation, uniformity of diameter and thickness, hardness, disintegration time and friability of tablets were conducted for standardization and the values obtained indicated the compliance with the pharmaceutical standards. HPLC profile of tablet and qualitative analysis of chemical constituents present in the tablet were also determined. Furthermore, tablets were also tested for the presence of pesticidal residue by comparing HPLC profile of pesticides and tablet in identical conditions and the result shown absence of pesticides in the formulation. These tablets can be used as an alternative of powder form of the given formulation and the findings will help to set the standards for future reference.

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