Evaluation of Diuretic Activity of Ethanolic Extract of Habb-e-Kaknaj (Physalis alkekengi Linn. Fruit) in Rat

Ghufran Ahmad, Wasim Ahmad, N.A. Khan, Shamshad Ahmad

Hippocratic Journal of Unani Medicine

Hippocratic Journal of Unani Medicine July - September 2013, Vol. 8 No. 3, Pages 1-9

Abstract

The present study was carried out to evaluate the diuretic activity of ethanolic extract of Habb-e-Kaknaj on healthy Wistar rats of either sex. The animals were kept on fasting for 8 hrs; thereafter they were administered normal saline (30 ml/kg) and divided into three groups

of six animals each. Animals in group I-III were treated with distilled water, furosemide (4 mg/kg) and ethanolic extract of Habb-e-Kaknaj (450 mg/kg), respectively. After respective treatment all the animals were kept separately in metabolic cages and the urine passed by them during a period of 6 hours was collected. In standard control and the test group the urine volume and urinary sodium and potassium level increased significantly when compared with plain control. The study demonstrated that ethanolic extracts fruits of Physalis alkekengi Linn. possesses significant diuretic effect.

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References