Hippocratic Journal of Unani Medicine

Hippocratic Journal of Unani Medicine April - June 2015, Vol. 10 No. 2, Pages 1-12

A Clinical Study to Evaluate the Efficacy of Unani Coded Drugs in Lymphatic Filariasis

Najmus Sehar, Syed Manzar Ahsan, M.I. Alam, M. Salam and Tasleem Ahmad

Abstract

The objective of the present study was to evaluate the efficacy of Unani coded drugs combination, UNIM-268 with and without Munzij-Mushil Therapy (M. M. Therapy) in the treatment of lymphatic filariasis, which is caused by the thread-like parasitic filarial worms. 154 selected patients were divided into Group-A (84 patients) and Group-B (70 patients) for their treatment without and with M. M. Therapy respectively. After treatment, the emprovements in clinical parameters of disease were observed in the patients of both groups. Filarial oedema volume score was found significantly reduced to 49.08% in Group A patients and 69.68% in Group-B patients. Improvements in lower limb volume in Grade-2 and Grade-3 filarial oedema were found 56% and 44% respectively in Group-A patients; 78.5% and 65.67% respectively in Group-B patients as compared to baseline. Comparatively better response of trial drugs were observed in Group-B patients. Pathological markers such as the level of TLC, total eosinophils counts, A.E.C. and ESR were found significantly reduced after treatment with the coded drugs. Biochemical parameters of Liver function and Kidney function tests were within the normal range after the treatment. Unani coded drugs combination, UNIM 268 was found clinically effective and safe in treatment of lymphatic filariasis.

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